This study aims to development and practice of infusing indigenous knowledge and epistemologies in curriculum. The three core elements of curriculum are as follows: ontology, value, and contextuality. An experiment study will be held in an aboriginal focus schools to evaluate the effects of the curriculum. In the first phase, a design principle will be developed via literature review, deep interview and field investigation. In the second phase, a knowledge and epistemologies based curriculum will be designed, experimental deign, preliminary data analysis and result will be developed to valid the learning effect of the learners. Refine the suggestions for guidelines of curriculum developing will be revealed as well.