In response to social changes and globalization, the Ministry of Education launched the 12-year basic education in 2011 and established a curriculum development mechanism. This mechanism was adjusted by the influence of the anti-curriculum social movements. In the national curriculum development it was from pluralism to unification. Although Social Studies and Natural Sciences, two domain-specific curriculums explored in this study, faced similar problem, such as: reduced hours and inconsistency between curriculum guidelines and actual operation, their curriculum guideline development teams were completely in the organization and operation. In addition, because the start-up time is different, the targets of the two were different. This study takes these two as examples to analyze problems of the curriculum development mechanism of 12-year basic education through specific examples.